Alexander Mankin
Distinguished Professor of Pharmaceutical Sciences
Biography
Alexander “Shura” Mankin studies the mechanisms of protein synthesis and drug resistance to develop new, superior antibiotics.
Mankin’s research focuses on the functions of the ribosome and how it can be inhibited by drugs. His laboratory has established modes of action of several important classes of antibiotics. His team has also engineered ribosomes for synthetic biology that do not exist in nature.
Mankin and his colleagues are working to discover how antibiotics bind to the ribosome, which churns out all the proteins a cell needs for survival, and how they interfere with its function.
SparkTalks: Alexander Mankin (video)
In the news
New antibiotic would make it more difficult for bacteria to develop drug resistance, UIC researchers say
Chicago Sun-Times
Areas of Expertise
Additional Information
In the News
Lasso-shaped antibiotic co-developed by UIC evades standard drug resistance
March 26, 2025
Dual-action antibiotic could make bacterial resistance nearly impossible
July 23, 2024
A compound from fruit flies could lead to new antibiotics
June 6, 2023